About one million Cubans are preparing to celebrate an open-air mass led by Pope Benedict XVI in Havana.
The Pope will hold the service in Revolution Square, on the final day of his visit to the country.
He will also meet the revolutionary leader and former President, Fidel Castro.
Fidel Castro, who also met Pope John Paul II when he visited the island in 1998, said he requested a few minutes with the Pope.
During the three-day visit, Pope Benedict has had to tread carefully, with activists calling for greater intervention from the Church to promote human rights.
In what appeared to be a reference to dissidents, the Pope offered a prayer for “the needs of those who suffer, of those who are deprived of freedom, those who are separated from their loved ones”.
And when he met President Raul Castro, the pontiff pushed for a bigger role for the Church and asked for Good Friday to be made a national holiday.
But he has no plans to meet members of the Cuban opposition, some of whom were barred from leaving their homes ahead of the Pope’s visit.